The effect of two dose phenylephrin for preventing hypotension during spinal anesthesia for cesarean delivery

Background: Spinal anesthesia-induced hypotension is one of the most complications which can cause many severe maternal and fetal complications. Therefore, prevention treatment spinal in pregnant women undergoing cesarean delivery play an important role. The use vasopressors effective method hypotensive prophylaxis phenylephrine currently first-line vasopressor choice to prevent this complication. aim study evaluate effectiveness safety two-dose for during delivery. Materials methods: In a randommized controlled clinical trial, 150 pregnants undregoing with anesthesia were randomly divided into three groups: Group I: as control group without (n = 50), II: 50µg intravenously bolus III: 75µg 50) immediately after induction anesthesia. Hypotension, defined decreasing systolic blood pressure > 20% baseline. incidence hypotension, levels side effects neonatal APGAR scores at 1 5 minutes. Results: was 44%, re-hypotension 16%. 28%, 2%. two groups both minute minutes same (p 0.05), all cases had 7. Conclusion: Phenylephrine intravenous doses 50 µg 75 are section. However, dose more than because lower rates recurrent (28% 2% vs 44% 16%, p < 0.05). addition, prophylactic didn’t detrimental adverses parturients their babies. Key words: Hypotensive prophylaxis, section, phenylephrin.